منابع مشابه
Elaboration of pyrimidine-specific nucleosidases by human lymphoblastoid cells of established cultures.
Pyrimidine-specific nucleosidases were released rapidly by human lymphoblastoid cells of established cultures when incubated under certain culture conditions having no adverse affect on their viability or morphology. Nucleosidase production was not restricted to any particular type of lymphoblastoid line; enzymes with a high level of activity were elaborated by cells of cultures initiated from ...
متن کاملElaboration of Pyrimidine-specific Nucleosidases by Human Lymphoblastoid Cells of Established Cultures1
pyrimidine-specific nucleosidases which degraded radiola beled precursors used for measuring DNA and RNA synthe sis. Results of studies reported herein, and findings of others, demonstrate that CLC as well as peripheral blood leuko cytes of healthy subjects and patients with uncontrolled lymphocytic or myelocytic leukmeia release nucleosidases, and possibly other enzymes, when these cells are m...
متن کاملPurification, characterization, and gene cloning of purine nucleosidase from Ochrobactrum anthropi.
A bacterium, Ochrobactrum anthropi, produced a large amount of a nucleosidase when cultivated with purine nucleosides. The nucleosidase was purified to homogeneity. The enzyme has a molecular weight of about 170,000 and consists of four identical subunits. It specifically catalyzes the irreversible N-riboside hydrolysis of purine nucleosides, the K(m) values being 11.8 to 56.3 microM. The optim...
متن کاملPyrimidine-2-carboxamide
In the crystal strucuture of the title compound, C(5)H(5)N(3)O, which was obtained upon recrystallization of 2-cyano-pyrimidine from aqueous sodium hydroxide, the amide group is twisted with respect to the aromatic ring by 24.9 (1)°. π-π stacking is observed between partially overlapped rings at a face-to-face separation of 3.439 (6) Å. The structure features a centrosymmetric pair of inter-mol...
متن کامل2-(2-Naphthyloxy)pyrimidine
In the title compound, C(14)H(10)N(2)O, the organic rings are inclined at an angle of 86.1 (1)°. The angle at the ether O atom is widened to 117.18 (14)°.
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1965
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)97572-1